What changed?

Market signal: Sandoz told the Financial Times it aims to introduce unbranded GLP-1s here with deep discounts as protections lapse—suggesting a real price correction on the horizon. While timelines depend on IP and regulatory steps, the message is clear: competition is coming. Reuters

Clinical guidance update: On Aug 11, 2025, CMAJ updated national guidance for adult obesity pharmacotherapy, emphasizing individualized care, pairing meds with behaviour change, and aligning goals with patient values and comorbidities. CMAJ

Why this matters for future physicians

1. Equity & coverage: Public plans will face pressure to define eligibility (BMI + comorbidities), step-therapy, and monitoring—who gets covered first, and how do we avoid widening disparities? CMAJ

2. Appropriate use & counseling: Expect conversations about realistic expectations (plateaus, weight regain if stopped), adverse effects, and long-term follow-up. CMAJ

3. System stewardship: If prices fall, uptake could surge—good for patients who need therapy, but it raises budget impact questions and the need for deprescribing plans when risks outweigh benefits. Reuters

Interview-ready talking points

Clinical: Indications, shared decision-making, and how you’d counsel a patient weighing benefits/risks and lifestyle supports. CMAJPolicy: Coverage criteria that prioritize highest-need groups; safeguards against unsafe compounded/black-market alternatives. ReutersEthics: Fair access across income, geography, and Indigenous communities; transparency about long-term commitment and side-effects. CMAJ

Quick compare: guidance vs. market reality

Guidance says: meds with behaviour change, individualized, ongoing reassessment.Market reality: affordability & availability drive adherence; lower prices could improve persistence but also require robust follow-up and realistic goal-setting. CMAJReuters

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References:
CMAJ, Pharmacotherapy for obesity management in adults: 2025 clinical practice guideline update (Aug 11, 2025). CMAJ
Reuters: Sandoz plans unbranded GLP-1s in Canada with deep discounts (Aug 5, 2025). Reuters

📌 Bonus PSA (admissions)

Dalhousie MD (2025/26 cycle): MCAT must have been written on/before Aug 9, 2025; Section 2 deadline Sept 3, 2025 (11:59 pm AT); CASPer test dates posted. Link and wording straight from Dal. Dalhousie University